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KMID : 0360220110520060679
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Journal of the Korean Ophthalmological Society
2011 Volume.52 No. 6 p.679 ~ p.689
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Long-term Clinical Outcomes of Femtosecond LASER-Assisted Descemet’s Stripping Endothelial Keratoplasty
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Moon Byung-Gil
Kim Jae-Hyung
Lee Joo-Eun
Kim Myoung-Joon
Kim Jae-Yong
Tchah Hung-Won
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Abstract
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Purpose: To evaluate the long-term clinical outcomes of femtosecond LASER-assisted Descemet’s stripping endothelial keratoplasty (DSEK).
Methods: The clinical results of endothelial keratopathy from 11 consecutive patients who were followed up for at least 12 months after femtosecond LASER-assisted DSEK were retrospectively analyzed. The best corrected visual acuities (BCVA), manifest refractions, intraocular pressures, and perioperative complications were evaluated preoperatively and up to 24 months after the femtosecond LASER-assisted DSEK.
Results: The average follow-up period was 18 months. Postoperative visual acuity had significantly improved from 1.26 (logMAR) to 0.80 (logMAR) at 3 months (p < 0.05) and this change was maintained during postoperative follow-up. All eyes underwent successful transplantation and the donor discs were well-attached. The mean endothelial cell density continued to decrease during the follow-up period. The donor-recipient stromal interface was the area where varying degree of haziness and birefringent particles were found.
Conclusions: The femtosecond LASER-assisted DSEK was effective in creating an endothelial donor disc which resulted in rapid visual recovery and low surgically-induced astigmatism. However, the operation caused rapid decrease in endothelial cell density which requires continuing further consideration by the physician.
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KEYWORD
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Anterior segment optical coherent tomography, Confocal microscopy, Femtosecond LASER-assisted Descetmet’s stripping endothelial keratoplasty
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